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Experimentally Generated
Generated systematically against validated disease targets using reproducible experimental protocols.
Science

Differences
Epigenetic proteins are not static structures. Their functional conformations emerge from interactions with chromatin, histone modifications, and other proteins in the complex.

Conventional Approaches
Conventional drug discovery studies isolated proteins. Static structures and PDB-trained AI models cannot capture the dynamic conformations that emerge within chromatin.

TippingPoint's Science
We recreate disease-specific chromatin states, capturing conformations that only emerge within functional biological systems.
Solution
Our platform reconstitutes three-dimensional chromatin states in vitro, capturing dynamic, multi-component conformations that static structures and PDB-trained AI models can't resolve.
Platform Output
Whether you're exploring a scientific collaboration, strategic partnership, or simply want to learn more about our platform, we'd love to start the conversation.